Lipid mediators in immune dysfunction after severe inflammation

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Lipid mediators in immune dysfunction after severe inflammation☆

Sepsis, trauma, burns, and major surgical procedures activate common systemic inflammatory pathways. Nosocomial infection, organ failure, and mortality in this patient population are associated with a quantitatively different reprioritization of the circulating leukocyte transcriptome to the initial inflammatory insult, greater in both magnitude and duration, and secondary to multiple observed ...

متن کامل

The role of neutrophils in immune dysfunction during severe inflammation.

Critically ill post-surgical, post-trauma and/or septic patients are characterised by severe inflammation. This immune response consists of both a pro- and an anti-inflammatory component. The pro-inflammatory component contributes to (multiple) organ failure whereas occurrence of immune paralysis predisposes to infections. Strikingly, infectious complications arise in these patients despite the...

متن کامل

Role of bioactive lipid mediators in obese adipose tissue inflammation and endocrine dysfunction.

White adipose tissue is recognized as an active endocrine organ implicated in the maintenance of metabolic homeostasis. However, adipose tissue function, which has a crucial role in the development of obesity-related comorbidities including insulin resistance and non-alcoholic fatty liver disease, is dysregulated in obese individuals. This review explores the physiological functions and molecul...

متن کامل

Exosomes: Mediators of Immune Regulation

Extracellular Vesicles, including exosomes, are small membrane fragments released from many cell types, like Mesenchymal Stem Cells (MSCs). They were recognized as a mechanism of intercellular communication. They can transfer proteins, lipids and nucleic acids to other cells. Thus, they have many physiological (angiogenesis, coagulation and tissue repair, etc.) and pathological (e.g. in autoimm...

متن کامل

Lipid Mediators in Skin Inflammation: Updates and Current Views

1Department of Biomedical Sciences, University of Siena, 53100 Siena, USA 2Department of Food and Nutrition, Research Institute of Human Ecology, Kyung Hee University, Seoul 130-701, Republic of Korea 3Laboratory of Tissue Engineering and Skin Pathophysiology, Istituto Dermopatico dell’Immacolata (IDI IRCCS), 00167 Rome, Italy 4University of Iowa Dows Institute for Dental Research, Iowa City, I...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Trends in Immunology

سال: 2014

ISSN: 1471-4906

DOI: 10.1016/j.it.2013.10.008